Methyltestosterone Feed Stability and Water Biodegradation Studies

Duration:
-

Drug Approval Research on 17a-Methyltestosterone

Description

The objectives for the fourth aquaculture drug project, Drug Approval Research on 17-a Methyltestosterone, include:

1.Develop a robust and validated high performance liquid chromatography (HPLC) and liquid chromatography-mass spectroscopy (LC-MS) method to measure 17α-methyltosterone (MT) in fish feed.

2.Conduct a series of stability studies on MT in fish feed.

3.Gain acceptance from the Center for Veterinary Medicine (CVM) for the series of stability studies.

4.Review and develop a LC-MS method for detecting MT in water.

5.Conduct a biodegradation study of MT in water.

6.Gain acceptance from CVM for the biodegradation study on MT.

Participants:

Principal Investigator/InstitutionObjectivesFunding
Ashok K. Marwah and Padma Marwah (University of Wisconsin - Madison)1 -6$169,362
Terence P. Barry (University of Wisconsin-Madison)2, 3, 5 & 6$ 54,315

Totals

$223,667

Project Outline (115K pdf file)

Termination Report (127K pdf file)

Project Number: 4

Award Amount

$223677.00

Award Number

2003-38500-12995