Methyltestosterone Feed Stability and Water Biodegradation Studies

Project

Drug Approval Research on 17a-Methyltestosterone


Description


The objectives for the fourth aquaculture drug project, Drug Approval Research on 17-a Methyltestosterone, include:


1.Develop a robust and validated high performance liquid chromatography (HPLC) and liquid chromatography-mass spectroscopy (LC-MS) method to measure 17α-methyltosterone (MT) in fish feed.


2.Conduct a series of stability studies on MT in fish feed.


3.Gain acceptance from the Center for Veterinary Medicine (CVM) for the series of stability studies.


4.Review and develop a LC-MS method for detecting MT in water.


5.Conduct a biodegradation study of MT in water.


6.Gain acceptance from CVM for the biodegradation study on MT.


Participants:






Principal Investigator/Institution Objectives Funding
Ashok K. Marwah and Padma Marwah (University of Wisconsin - Madison) 1 -6 $169,362
Terence P. Barry (University of Wisconsin-Madison) 2, 3, 5 & 6 $ 54,315
                                   Totals   $223,667

Project Outline (115K pdf file)


Report (127K pdf file)


Project Number: 4

Duration: 
06/01/2004 to 12/31/2005
Award Amount: 
$223,677.00
Award Number: 
2003-38500-12995
Project Type: